Members of this family have several predicted transmembrane helices. One member of the family has been characterised as protein PGR (AtPGR). PGR is suggested to be a potential glucose-responsive regulator in carbohydrate metabolism in plants. This entry also includes protein VTE6, which is a Pphytyl-phosphate kinase catalysing the conversion of phytyl-monophosphate to phytyl-diphosphate [[cite:PUB00092523]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00092523":{"PMID":26452599,"ISBN":null,"volume":"27","issue":"10","year":2015,"title":"Remobilization of Phytol from Chlorophyll Degradation Is Essential for Tocopherol Synthesis and Growth of Arabidopsis.","URL":null,"raw_pages":"2846-59","medline_journal":"Plant Cell","ISO_journal":"Plant Cell","authors":["Vom Dorp K","Holzl G","Plohmann C","Eisenhut M","Abraham M","Weber AP","Hanson AD","Dormann P."],"DOI_URL":"https://doi.org/10.1105/tpc.15.00395"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":97,"interactions":0,"matches":6228,"pathways":0,"proteins":6136,"proteomes":4750,"sets":0,"structural_models":{"alphafold":4924},"structures":0,"taxa":11004},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":249,"alignment:full":4299},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}