{"metadata":{"accession":"PF01939","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR048301","hierarchy":null,"name":{"name":"Endonuclease NucS C-terminal domain","short":"NucS_C"},"description":[{"text":"<p>Endonuclease NucS cleaves both 3' and 5' ssDNA extremities of branched DNA structures and it binds to ssDNA [[cite:PUB00060574],[cite:PUB00052724]]. This entry represents the C-terminal domain of NucS.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00052724":{"PMID":19609302,"ISBN":null,"volume":"28","issue":"16","year":2009,"title":"Structure and function of a novel endonuclease acting on branched DNA substrates.","URL":null,"raw_pages":"2479-89","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Ren B","Kuhn J","Meslet-Cladiere L","Briffotaux J","Norais C","Lavigne R","Flament D","Ladenstein R","Myllykallio H."],"DOI_URL":"http://dx.doi.org/10.1038/emboj.2009.192"},"PUB00060574":{"PMID":22431731,"ISBN":null,"volume":"287","issue":"19","year":2012,"title":"Modulation of the Pyrococcus abyssi NucS endonuclease activity by replication clamp at functional and structural levels.","URL":null,"raw_pages":"15648-60","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Creze C","Ligabue A","Laurent S","Lestini R","Laptenok SP","Khun J","Vos MH","Czjzek M","Myllykallio H","Flament D."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M112.346361"}},"set_info":{"accession":"CL0236","name":"PDDEXK"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":24,"interactions":0,"matches":5068,"pathways":0,"proteins":5060,"proteomes":4806,"sets":1,"structural_models":{"alphafold":3150},"structures":7,"taxa":6631},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":2506},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}