{"metadata":{"accession":"PF01894","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR001602","hierarchy":null,"name":{"name":"UPF0047 protein YjbQ-like","short":"YjbQ"},"description":[{"text":"<p>This family includes YjbQ from Escherichia coli, its orthologue from Pyrococcus furiosus and similar sequences. These proteins have been shown to have sufficient thiamine phosphate synthase activity to complement thiE mutants. However, it is presumed that this is a secondary activity, and the primary function of the YjbQ family enzyme remains unknown [[cite:PUB00101019],[cite:PUB00101020]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101020":{"PMID":18178222,"ISBN":null,"volume":"376","issue":"3","year":2008,"title":"Sensitive genome-wide screen for low secondary enzymatic activities: the YjbQ family shows thiamin phosphate synthase activity.","URL":null,"raw_pages":"839-53","medline_journal":"J Mol Biol","ISO_journal":"J Mol Biol","authors":["Morett E","Saab-Rincon G","Olvera L","Olvera M","Flores H","Grande R."],"DOI_URL":null},"PUB00101019":{"PMID":21119630,"ISBN":null,"volume":"6","issue":null,"year":2010,"title":"Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.","URL":null,"raw_pages":"436","medline_journal":"Mol Syst Biol","ISO_journal":"Mol Syst Biol","authors":["Kim J","Kershner JP","Novikov Y","Shoemaker RK","Copley SD."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":83,"interactions":0,"matches":14162,"pathways":0,"proteins":14125,"proteomes":12151,"sets":0,"structural_models":{"alphafold":9964},"structures":9,"taxa":20399},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":436,"alignment:full":8127},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"1ve0","name":"Crystal structure of uncharacterized protein ST2072 from Sulfolobus tokodaii"}}}