{"metadata":{"accession":"PF01875","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR002737","hierarchy":null,"name":{"name":"Memo-like protein","short":"Memo"},"description":[{"text":"<p>This family contains members from all branches of life. The molecular function of this protein is unknown, but Memo (mediator of ErbB2-driven cell motility) a human protein is included in this family [[cite:PUB00044702]]. It has been suggested that Memo controls cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton [[cite:PUB00044702]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044702":{"PMID":15156151,"ISBN":null,"volume":"6","issue":"6","year":2004,"title":"Memo mediates ErbB2-driven cell motility.","URL":null,"raw_pages":"515-22","medline_journal":"Nat Cell Biol","ISO_journal":"Nat. Cell Biol.","authors":["Marone R","Hess D","Dankort D","Muller WJ","Hynes NE","Badache A."],"DOI_URL":"http://dx.doi.org/10.1038/ncb1134"}},"set_info":{"accession":"CL0283","name":"LigB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":85,"interactions":0,"matches":6527,"pathways":0,"proteins":6407,"proteomes":5074,"sets":1,"structural_models":{"alphafold":5333},"structures":5,"taxa":12387},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":10,"alignment:full":4714},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"7m8h","name":"Structure of Memo1 C244S metal binding site mutant at 1.75A"}}}