It has been suggested that this gene family be designated tps (for terpene synthase) [[cite:PUB00002995]]. It has been split into six subgroups on the basis of phylogeny, called tpsa-tpsf. tpsa includes vetispiridiene synthase [swissprot:Q39979], 5-epi- aristolochene synthase, [swissprot:Q40577] and (+)-delta-cadinene synthase [swissprot:P93665]. tpsb includes (-)-limonene synthase, [swissprot:Q40322]. tpsc includes kaurene synthase A, [swissprot:O04408]. tpsd includes taxadiene synthase, [swissprot:Q41594], pinene synthase, [swissprot:O24475] and myrcene synthase, [swissprot:O24474]. tpse includes kaurene synthase B. tpsf includes linalool synthase.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Terpene_synthase_N_terminal_domain","extract":"In molecular biology, this protein domain belongs to the terpene synthase family (TPS). Its role is to synthesize terpenes, which are part of primary metabolism, such as sterols and\ncarotene, and also part of the secondary metabolism. This entry will focus on the N terminal domain of the TPS protein.
","thumbnail":null}],"literature":{"PUB00002995":{"PMID":9268308,"ISBN":null,"volume":"272","issue":"35","year":1997,"title":"Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase.","URL":null,"raw_pages":"21784-92","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Bohlmann J","Steele CL","Croteau R."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.272.35.21784"}},"set_info":{"accession":"CL0059","name":"6_Hairpin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":263,"interactions":0,"matches":23168,"pathways":0,"proteins":22613,"proteomes":369,"sets":1,"structural_models":{"alphafold":19261,"bfvd":0},"structures":94,"taxa":1911},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":153,"alignment:full":11218},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}