{"metadata":{"accession":"PF01256","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR000631","hierarchy":null,"name":{"name":"NAD(P)H-hydrate dehydratase","short":"Carb_kinase"},"description":[{"text":"<p>Hydration of NAD(P)H to NAD(P)HX, which inhibits several dehydrogenases, is corrected by an ATP-dependent dehydratase and an  epimerase. The ATP-dependent dehydratase has been identified as the  product of the vertebrate Carkd (carbohydrate kinase domain) gene  [[cite:PUB00073185],[cite:PUB00100876]]. Variants of this enzyme leads to deficient NADHX repair  mitochondrial dysfunction in humans, associated with a lethal  neurometabolic disorder in early childhood [[cite:PUB00100876]]. In E. coli, it is  found as the C-terminal domain of a bifunctional enzyme (YjeF) that  also includes the epimerase and uses ADP instead of ATP [[cite:PUB00060794]]. These  enzymes are widespread in eukaryotes, prokaryotes, and archaea.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"CARKD","extract":"<p><b>Carbohydrate kinase domain containing protein</b>, encoded by <b>CARKD</b> gene, is a human protein of unknown function. The CARKD gene encodes proteins with a predicted mitochondrial propeptide (mCARKD), a signal peptide (spCARKD) or neither of them (cCARKD). Confocal microscopy analysis of transfected CHO cells indicated that cCARKD remains in the cytosol, whereas mCARKD and spCARKD are targeted to the mitochondria and the endoplasmic reticulum respectively. The protein is conserved throughout many species, and has predicted orthologs through eukaryotes, bacteria, and archea.</p>","thumbnail":"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"}],"literature":{"PUB00060794":{"PMID":21994945,"ISBN":null,"volume":"286","issue":"48","year":2011,"title":"Extremely 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