{"metadata":{"accession":"PF01171","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR011063","hierarchy":null,"name":{"name":"PP-loop domain","short":"ATP_bind_3"},"description":[{"text":"<p>The structure of tRNA(Ile)-lysidine synthetase consists of an N-terminal dinucleotide-binding fold domain (NTD), and a C-terminal globular domain (CTD). The structure of the NTD closely resembles that of a P-loop \"N-type\" ATP pyrophosphatase [[cite:PUB00034489]]. These proteins belong to the PP-loop superfamily [[cite:PUB00014303]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00014303":{"PMID":7731953,"ISBN":null,"volume":"20","issue":"4","year":1994,"title":"A P-loop-like motif in a widespread ATP pyrophosphatase domain: implications for the evolution of sequence motifs and enzyme activity.","URL":null,"raw_pages":"347-55","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Bork P","Koonin EV."],"DOI_URL":"http://dx.doi.org/10.1002/prot.340200407"},"PUB00034489":{"PMID":15894617,"ISBN":null,"volume":"102","issue":"21","year":2005,"title":"Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.","URL":null,"raw_pages":"7487-92","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Nakanishi K","Fukai S","Ikeuchi Y","Soma A","Sekine Y","Suzuki T","Nureki O."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.0501003102"}},"set_info":{"accession":"CL0039","name":"HUP"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":200,"interactions":0,"matches":34389,"pathways":0,"proteins":33613,"proteomes":21356,"sets":1,"structural_models":{"alphafold":23049},"structures":16,"taxa":34246},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":14,"alignment:full":19225},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}