{"metadata":{"accession":"PF01128","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR034683","hierarchy":null,"name":{"name":"2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase","short":"IspD"},"description":[{"text":"<p>Members of this family are enzymes which catalyse the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from cytidine triphosphate and 2-C-methyl-D-erythritol 4-phosphate (MEP) [[cite:PUB00011034]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase","extract":"<p><b>2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</b> is an enzyme that catalyzes the chemical reaction:</p>","thumbnail":null}],"literature":{"PUB00011034":{"PMID":10518523,"ISBN":null,"volume":"96","issue":"21","year":1999,"title":"Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol.","URL":null,"raw_pages":"11758-63","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Rohdich F","Wungsintaweekul J","Fellermeier M","Sagner S","Herz S","Kis K","Eisenreich W","Bacher A","Zenk MH."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.96.21.11758"}},"set_info":{"accession":"CL0110","name":"GT-A"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":60,"interactions":0,"matches":19791,"pathways":0,"proteins":19574,"proteomes":16789,"sets":1,"structural_models":{"alphafold":13015},"structures":56,"taxa":26255},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":10802},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2ycm","name":"Inhibitors of herbicidal target IspD"}}}