{"metadata":{"accession":"TIGR03264","entry_id":null,"type":"family","go_terms":null,"source_database":"ncbifam","member_databases":null,"integrated":"IPR007687","hierarchy":null,"name":{"name":"methyl-coenzyme M reductase I operon protein C","short":"met_CoM_red_C"},"description":[{"text":"<p>Members of this protein family are protein C, a non-structural protein, of the operon for methyl coenzyme M reductase, also called coenzyme-B sulfoethylthiotransferase (EC 2.8.4.1). That enzyme, with alpha, beta, and gamma subunits, catalyzes the last step in methanogenesis; it has several modified sites, so accessory proteins are expected. Several methanogens have encode two such enzymes, designated I and II; this protein occurs only operons of type I. The precise function is unknown.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00043078":{"PMID":8177216,"ISBN":null,"volume":"243","issue":"2","year":1994,"title":"Characterization and phylogeny of mcrII, a gene cluster encoding an isoenzyme of methyl coenzyme M reductase from hyperthermophilic Methanothermus fervidus.","URL":null,"raw_pages":"198-206","medline_journal":"Mol Gen Genet","ISO_journal":"Mol. Gen. Genet.","authors":["Lehmacher A","Klenk HP."],"DOI_URL":null},"PUB00013556":{"PMID":8359675,"ISBN":null,"volume":"111","issue":"1","year":1993,"title":"Identification of the mcrC gene product in Methanococcus vannielii.","URL":null,"raw_pages":"129-34","medline_journal":"FEMS Microbiol Lett","ISO_journal":"FEMS Microbiol. Lett.","authors":["Stroup D","Reeve JN."],"DOI_URL":"http://dx.doi.org/10.1016/0378-1097(93)90193-6"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":0,"interactions":0,"matches":247,"pathways":0,"proteins":247,"proteomes":153,"sets":0,"structural_models":{"alphafold":230,"bfvd":0},"structures":3,"taxa":371},"entry_annotations":{"hmm":0,"logo":0},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}