"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"cd22293"	"{'subfamilies': 0, 'domain_architectures': 0, 'interactions': 0, 'matches': 530, 'pathways': 0, 'proteins': 530, 'proteomes': 469, 'sets': 0, 'structural_models': {'alphafold': 502, 'bfvd': 0}, 'structures': 3, 'taxa': 1568}"	"{}"	"[{'text': '<p>SHLD3, also called REV7-interacting novel NHEJ regulator 1, or Shield complex subunit 3, is a component of the shieldin complex, which plays an important role in the repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. SHLD3 mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. The model corresponds to the N-terminal REV7-binding domain of SHLD3, which contains a REV7-binding FXPWFP motif. [[cite:PUB00089626], [cite:PUB00147810]]</p>', 'llm': False, 'checked': False, 'updated': False}]"	""	""	""	""	False	False	False	"{'PUB00147810': {'PMID': 32332881, 'ISBN': None, 'volume': '11', 'issue': '1', 'year': 2020, 'title': 'Molecular basis for assembly of the shieldin complex and its implications for NHEJ.', 'URL': None, 'raw_pages': '1972', 'medline_journal': 'Nat Commun', 'ISO_journal': 'Nat Commun', 'authors': ['Liang L', 'Feng J', 'Zuo P', 'Yang J', 'Lu Y', 'Yin Y.'], 'DOI_URL': None}, 'PUB00089626': {'PMID': 29656893, 'ISBN': None, 'volume': '173', 'issue': '4', 'year': 2018, 'title': 'DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.', 'URL': None, 'raw_pages': '972-988.e23', 'medline_journal': 'Cell', 'ISO_journal': 'Cell', 'authors': ['Gupta R', 'Somyajit K', 'Narita T', 'Maskey E', 'Stanlie A', 'Kremer M', 'Typas D', 'Lammers M', 'Mailand N', 'Nussenzweig A', 'Lukas J', 'Choudhary C.'], 'DOI_URL': 'https://doi.org/10.1016/j.cell.2018.03.050'}}"	""	"{'name': 'N-terminal REV7-binding domain of Shieldin complex subunit 3 (SHLD3) and similar proteins', 'short': 'RBD_SHLD3_N'}"	""	""	""	"cdd"	"domain"	""