"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"cd16779"	"{'subfamilies': 0, 'domain_architectures': 0, 'interactions': 0, 'matches': 518, 'pathways': 0, 'proteins': 518, 'proteomes': 274, 'sets': 1, 'structural_models': {'alphafold': 465, 'bfvd': 0}, 'structures': 2, 'taxa': 1001}"	"{}"	"[{'text': '<p>LNX1, also known as numb-binding protein 1 or PDZ domain-containing RING finger protein 2, is a PDZ domain-containing RING-type E3 ubiquitin ligase responsible for the ubiquitination and degradation of Numb, a component of the Notch signaling pathway that functions in the specification of cell fates during development and is known to control cell numbers during neurogenesis in vertebrates. LNX1 contains an N-terminal modified C3HC3D-type RING-HC finger, a NPAY motif for Numb-LNX interaction, and four PDZ domains necessary for the binding of substrates, including CAR, ErbB2, SKIP, JAM4, CAST, c-Src, Claudins, RhoC, KCNA4, PAK6, PLEKHG5, PKC-alpha1, TYK2, PDZ-binding kinase (PBK), LNX2, and itself. [[cite:PUB00136505], [cite:PUB00136506], [cite:PUB00136507], [cite:PUB00033494]]</p>', 'llm': False, 'checked': False, 'updated': False}]"	""	""	""	""	False	False	False	"{'PUB00136505': {'PMID': 25200495, 'ISBN': None, 'volume': '552', 'issue': '1', 'year': 2014, 'title': 'Tight, cell type-specific control of LNX expression in the nervous system, at the level of transcription, translation and protein stability.', 'URL': None, 'raw_pages': '39-50', 'medline_journal': 'Gene', 'ISO_journal': 'Gene', 'authors': ['Lenihan JA', 'Saha O', 'Mansfield LM', 'Young PW.'], 'DOI_URL': None}, 'PUB00033494': {'PMID': 16002321, 'ISBN': None, 'volume': '37', 'issue': '11', 'year': 2005, 'title': 'Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas.', 'URL': None, 'raw_pages': '2273-83', 'medline_journal': 'Int J Biochem Cell Biol', 'ISO_journal': 'Int. J. Biochem. Cell Biol.', 'authors': ['Chen J', 'Xu J', 'Zhao W', 'Hu G', 'Cheng H', 'Kang Y', 'Xie Y', 'Lu Y.'], 'DOI_URL': 'http://dx.doi.org/10.1016/j.biocel.2005.02.028'}, 'PUB00136506': {'PMID': 22889411, 'ISBN': None, 'volume': '11', 'issue': '10', 'year': 2012, 'title': 'Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.', 'URL': None, 'raw_pages': '4847-62', 'medline_journal': 'J Proteome Res', 'ISO_journal': 'J Proteome Res', 'authors': ['Guo Z', 'Song E', 'Ma S', 'Wang X', 'Gao S', 'Shao C', 'Hu S', 'Jia L', 'Tian R', 'Xu T', 'Gao Y.'], 'DOI_URL': None}, 'PUB00136507': {'PMID': 21827680, 'ISBN': None, 'volume': '11', 'issue': None, 'year': 2011, 'title': 'Molecular evolution of the LNX gene family.', 'URL': None, 'raw_pages': '235', 'medline_journal': 'BMC Evol Biol', 'ISO_journal': 'BMC Evol Biol', 'authors': ['Flynn M', 'Saha O', 'Young P.'], 'DOI_URL': None}}"	""	"{'name': 'Modified RING finger, HC subclass (C3HC3D-type), found in ligand of numb protein X 1 (LNX1)', 'short': 'mRING-HC-C3HC3D_LNX1'}"	""	""	"{'accession': 'cl17238', 'name': 'RING_Ubox'}"	"cdd"	"domain"	""