HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "IPR047450",
"entry_id": null,
"type": "domain",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"cdd": {
"cd20436": "first Tudor domain found in Tudor domain-containing protein 15 (TDRD15) and similar proteins"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR002999",
"name": "Tudor domain",
"type": "Domain",
"children": [
{
"accession": "IPR047367",
"name": "A-kinase anchor protein 1, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047376",
"name": "Tudor domain-containing protein 1, first Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047377",
"name": "Tudor domain-containing protein 1, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047378",
"name": "Tudor domain-containing protein 1, third Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047379",
"name": "Tudor domain-containing protein 3, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047380",
"name": "Tudor domain-containing protein 2-like, tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047383",
"name": "Tudor domain-containing protein 8, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047384",
"name": "Tudor domain-containing protein 9, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047386",
"name": "Tudor domain-containing protein 11, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047390",
"name": "Tudor domain-containing protein 12, first Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047395",
"name": "Ribonuclease Tudor 1/2, Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047396",
"name": "Protein vreteno, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047444",
"name": "TDRD6, first Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047445",
"name": "TDRD6, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047446",
"name": "TDRD6, fourth Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047447",
"name": "TDRD6, third Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047448",
"name": "TDRD7, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047449",
"name": "TDRD7, third Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047450",
"name": "TDRD15, first Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047452",
"name": "TDRD15, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047454",
"name": "TDRD15, third Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047455",
"name": "TDRD15, fourth Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047457",
"name": "TDRD15, seventh Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047459",
"name": "TDRD15, sixth Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047460",
"name": "TDRD15, fifth Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047474",
"name": "ARID4B, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047847",
"name": "RING finger protein 17-like, second Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047848",
"name": "RING finger protein 17-like, third Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047849",
"name": "RING finger protein 17-like, fourth Tudor domain",
"type": "Domain",
"children": []
},
{
"accession": "IPR047850",
"name": "RING finger protein 17-like, fifth Tudor domain",
"type": "Domain",
"children": []
}
]
},
"name": {
"name": "TDRD15, first Tudor domain",
"short": "Tudor_TDRD15_rpt1"
},
"description": [
{
"text": "<p>This entry represents the first Tudor domain of human TDRD15 and similar sequences mainly found in vertebrates. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions [[cite:PUB00103160], [cite:PUB00091520]].</p>",
"llm": false,
"checked": false,
"updated": false
},
{
"text": "<p>TDRD15 is an uncharacterised Tudor domain-containing protein that contains seven Tudor domains.</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00091520": {
"PMID": 24035451,
"ISBN": null,
"volume": "38",
"issue": "11",
"year": 2013,
"title": "Tudor: a versatile family of histone methylation 'readers'.",
"URL": null,
"raw_pages": "546-55",
"medline_journal": "Trends Biochem Sci",
"ISO_journal": "Trends Biochem. Sci.",
"authors": [
"Lu R",
"Wang GG."
],
"DOI_URL": "https://doi.org/10.1016/j.tibs.2013.08.002"
},
"PUB00103160": {
"PMID": 20728048,
"ISBN": null,
"volume": "20",
"issue": "16",
"year": 2010,
"title": "Tudor domain.",
"URL": null,
"raw_pages": "R666-7",
"medline_journal": "Curr Biol",
"ISO_journal": "Curr Biol",
"authors": [
"Lasko P."
],
"DOI_URL": null
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 297,
"pathways": 0,
"proteins": 297,
"proteomes": 219,
"sets": 0,
"structural_models": {
"alphafold": 12,
"bfvd": 0
},
"structures": 0,
"taxa": 816
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}