"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"IPR042216"	"{'subfamilies': 0, 'domain_architectures': 0, 'interactions': 0, 'matches': 17308, 'pathways': 0, 'proteins': 13240, 'proteomes': 7357, 'sets': 0, 'structural_models': {'alphafold': 10634, 'bfvd': 2}, 'structures': 32, 'taxa': 15063}"	"{}"	"[{'text': '<p>CDGSH iron-sulfur domains (CISDs) are classified into seven major types and are widely distributed throughout the three domains of life [[cite:PUB00056986]]. This superfamily represents the C-terminal domain found in the human CISD protein mitoNEET, also designated CSD1, an iron-containing integral protein of the outer mitochondrial membrane (OMM). MitoNEET contains two domains: a β-cap region and a cluster-binding domain, containing the CDGSH motif, that coordinates two acid-labile 2Fe-2S clusters (one bound to each protomer) [[cite:PUB00042908]]. The CDGSH iron-sulphur domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates [[cite:PUB00044559], [cite:PUB00042908]]. The whole protein regulates oxidative capacity and might be involved in electron transfer.</p>', 'llm': False, 'checked': False, 'updated': False}]"	""	""	"{'accession': 'IPR042216', 'name': 'MitoNEET, CDGSH iron-sulfur domain', 'type': 'Homologous_superfamily', 'children': []}"	""	False	False	False	"{'PUB00056986': {'PMID': 21949752, 'ISBN': None, 'volume': '6', 'issue': '9', 'year': 2011, 'title': 'Structure and molecular evolution of CDGSH iron-sulfur domains.', 'URL': None, 'raw_pages': 'e24790', 'medline_journal': 'PLoS One', 'ISO_journal': 'PLoS ONE', 'authors': ['Lin J', 'Zhang L', 'Lai S', 'Ye K.'], 'DOI_URL': 'http://dx.doi.org/10.1371/journal.pone.0024790'}, 'PUB00042908': {'PMID': 17766440, 'ISBN': None, 'volume': '104', 'issue': '36', 'year': 2007, 'title': 'MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone.', 'URL': None, 'raw_pages': '14342-7', 'medline_journal': 'Proc Natl Acad Sci U S A', 'ISO_journal': 'Proc. Natl. Acad. Sci. U.S.A.', 'authors': ['Paddock ML', 'Wiley SE', 'Axelrod HL', 'Cohen AE', 'Roy M', 'Abresch EC', 'Capraro D', 'Murphy AN', 'Nechushtai R', 'Dixon JE', 'Jennings PA.'], 'DOI_URL': 'http://dx.doi.org/10.1073/pnas.0707189104'}, 'PUB00044559': {'PMID': 17584744, 'ISBN': None, 'volume': '282', 'issue': '33', 'year': 2007, 'title': 'The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.', 'URL': None, 'raw_pages': '23745-9', 'medline_journal': 'J Biol Chem', 'ISO_journal': 'J. Biol. Chem.', 'authors': ['Wiley SE', 'Paddock ML', 'Abresch EC', 'Gross L', 'van der Geer P', 'Nechushtai R', 'Murphy AN', 'Jennings PA', 'Dixon JE.'], 'DOI_URL': 'http://dx.doi.org/10.1074/jbc.C700107200'}}"	"{'cathgene3d': {'G3DSA:3.40.5.90': 'CDGSH iron-sulfur domain, mitoNEET-type'}}"	"{'name': 'MitoNEET, CDGSH iron-sulfur domain', 'short': 'MitoNEET_CISD'}"	"[{'accession': 'IPR018967', 'name': 'Iron-binding zinc finger, CDGSH type', 'type': 'domain'}, {'accession': 'IPR017123', 'name': 'Uncharacterised conserved protein UCP037159', 'type': 'family'}]"	"{'accession': '3tbo', 'name': 'Crystal structure of a type 3 CDGSH iron-sulfur protein.'}"	""	"interpro"	"homologous_superfamily"	""