"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"IPR039095"	"{'subfamilies': 0, 'domain_architectures': 0, 'interactions': 0, 'matches': 282, 'pathways': 0, 'proteins': 282, 'proteomes': 213, 'sets': 0, 'structural_models': {'alphafold': 249, 'bfvd': 0}, 'structures': 0, 'taxa': 835}"	"{}"	"[{'text': '<p>TCF-19, also termed transcription factor SC1, was identified as a putative trans-activating factor with expression beginning at the late G1-S boundary in dividing cells [[cite:PUB00088919]]. It also functions as a novel islet factor necessary for proliferation and survival in the INS-1 beta cell line. It plays an important role in susceptibility to both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM); it has been suggested that it may positively impact beta cell mass under conditions of beta cell stress and increased insulin demand [[cite:PUB00088921]].</p>\n\n<p>TCF-19 contains an N-terminal fork head association domain (FHA), a proline rich region, and a C-terminal plant homeodomain (PHD) finger. The FHA domain may serve as a nuclear signaling domain or as a phosphoprotein binding domain. The proline rich region is a common characteristic of trans-activating factors. The PHD finger may allow TCF-19 to interact with chromatin via methylated histone H3 [[cite:PUB00048339]].</p>', 'llm': False, 'checked': False, 'updated': False}]"	""	"[{'identifier': 'GO:0010468', 'name': 'regulation of gene expression', 'category': {'code': 'P', 'name': 'biological_process'}}]"	"{'accession': 'IPR001965', 'name': 'Zinc finger, PHD-type', 'type': 'Domain', 'children': [{'accession': 'IPR019787', 'name': 'Zinc finger, PHD-finger', 'type': 'Domain', 'children': [{'accession': 'IPR028940', 'name': 'Bromodomain adjacent to zinc finger domain protein 2A, PHD zinc finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR031202', 'name': 'PHD finger protein 1, PHD finger 1', 'type': 'Domain', 'children': []}, {'accession': 'IPR037373', 'name': 'Transcription intermediary factor 1-beta, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR037877', 'name': 'HMT2C, PHD3', 'type': 'Domain', 'children': []}, {'accession': 'IPR039054', 'name': 'Int12, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR039546', 'name': 'Jade-1, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR039548', 'name': 'JADE2, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR039550', 'name': 'JADE3, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041947', 'name': 'PHF13, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR042008', 'name': 'BRPF1, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042009', 'name': 'BRPF2, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042010', 'name': 'ATX1/2, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042011', 'name': 'ATX3/4/5, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042014', 'name': 'MTF2, PHD domain 1', 'type': 'Domain', 'children': []}, {'accession': 'IPR042019', 'name': 'ING2, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042020', 'name': 'ING3, PHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042023', 'name': 'KMT2A, PHD domain 1', 'type': 'Domain', 'children': []}, {'accession': 'IPR042025', 'name': 'KMT2A, PHD domain 2', 'type': 'Domain', 'children': []}, {'accession': 'IPR044075', 'name': 'PRKCBP1, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR044104', 'name': 'Alfin1-like, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR044133', 'name': 'KMT2A, PHD domain 3', 'type': 'Domain', 'children': []}, {'accession': 'IPR045876', 'name': 'Pathogenesis-related homeodomain protein, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR046999', 'name': 'KMT2D, PHD5 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047000', 'name': 'KMT2D, PHD3 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047003', 'name': 'KMT2C, PHD4 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047004', 'name': 'KMT2C, PHD2 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047005', 'name': 'KMT2C, PHD6 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047256', 'name': 'Tyrosine-protein kinase BAZ1B, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047426', 'name': 'Histone-lysine N-methyltransferase NSD1 / NSD2, first PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047430', 'name': 'Nuclear receptor-binding SET domain-containing protein 1, fourth PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047467', 'name': 'E3 ubiquitin-protein ligase UHRF2, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047970', 'name': 'Lysine-specific demethylase 5A, second PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047972', 'name': 'Lysine-specific demethylase 5A, third PHD-finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047973', 'name': 'Lysine-specific demethylase 5A, first PHD-finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047978', 'name': 'Lysine-specific demethylase 5B, first PHD-finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047979', 'name': 'Lysine-specific demethylase 5B, third PHD-finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR049781', 'name': 'AF-10/AF-17, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR058054', 'name': 'PHD finger protein MALE STERILITY 1-like, Zinc finger', 'type': 'Domain', 'children': []}]}, {'accession': 'IPR034732', 'name': 'Extended PHD (ePHD) domain', 'type': 'Domain', 'children': [{'accession': 'IPR039549', 'name': 'JADE2, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041955', 'name': 'ATX3/4/5, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041956', 'name': 'ATX1/2, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041958', 'name': 'KMT2A, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041959', 'name': 'KMT2B, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041961', 'name': 'KMT2D, ePHD1 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041964', 'name': 'KMT2D, ePHD2 domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR041967', 'name': 'KMT2C, ePHD1', 'type': 'Domain', 'children': []}, {'accession': 'IPR041968', 'name': 'KMT2C, ePHD2', 'type': 'Domain', 'children': []}, {'accession': 'IPR041972', 'name': 'Transcription factor 20, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042004', 'name': 'BRPF2, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042005', 'name': 'BRPF3, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042013', 'name': 'PHF7/G2E3, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR042061', 'name': 'Peregrin, ePHD domain', 'type': 'Domain', 'children': []}, {'accession': 'IPR047482', 'name': 'Lysine-specific demethylase 4A, extended PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR049775', 'name': 'AF-10, extended PHD finger', 'type': 'Domain', 'children': []}]}, {'accession': 'IPR039095', 'name': 'Transcription factor 19, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR042015', 'name': 'MTF2, PHD domain 2', 'type': 'Domain', 'children': []}, {'accession': 'IPR042017', 'name': 'PHF19, PHD domain 2', 'type': 'Domain', 'children': []}, {'accession': 'IPR043319', 'name': 'ASH1-like, PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047010', 'name': 'PHD finger protein 1, PHD finger 2', 'type': 'Domain', 'children': []}, {'accession': 'IPR047432', 'name': 'Nuclear receptor-binding SET domain-containing protein 1, fifth PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047442', 'name': 'Nuclear SET domain-containing protein 2, fifth PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047458', 'name': 'Histone-lysine N-methyltransferase NSD3, fourth PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047527', 'name': 'Histone-lysine N-methyltransferase NSD3, fifth PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR055197', 'name': 'Histone-lysine N-methyltransferase NSD-like, variant PHD zinc finger', 'type': 'Domain', 'children': [{'accession': 'IPR047429', 'name': 'Nuclear receptor-binding SET domain-containing protein 1, third PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047441', 'name': 'Nuclear SET domain-containing protein 2, third PHD finger', 'type': 'Domain', 'children': []}]}, {'accession': 'IPR055198', 'name': 'Histone-lysine N-methyltransferase NSD-like, PHD zinc finger', 'type': 'Domain', 'children': [{'accession': 'IPR047428', 'name': 'Nuclear receptor-binding SET domain-containing protein 1, second PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047439', 'name': 'Nuclear SET domain-containing protein 2, second PHD finger', 'type': 'Domain', 'children': []}, {'accession': 'IPR047456', 'name': 'Histone-lysine N-methyltransferase NSD3, second PHD finger', 'type': 'Domain', 'children': []}]}, {'accession': 'IPR059102', 'name': 'PHF7/G2E3-like, PHD zinc finger domain', 'type': 'Domain', 'children': []}]}"	""	False	False	False	"{'PUB00048339': {'PMID': 19430464, 'ISBN': None, 'volume': '459', 'issue': '7248', 'year': 2009, 'title': 'Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.', 'URL': None, 'raw_pages': '847-51', 'medline_journal': 'Nature', 'ISO_journal': 'Nature', 'authors': ['Wang GG', 'Song J', 'Wang Z', 'Dormann HL', 'Casadio F', 'Li H', 'Luo JL', 'Patel DJ', 'Allis CD.'], 'DOI_URL': 'http://dx.doi.org/10.1038/nature08036'}, 'PUB00088921': {'PMID': 23860123, 'ISBN': None, 'volume': '305', 'issue': '5', 'year': 2013, 'title': 'Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.', 'URL': None, 'raw_pages': 'E600-10', 'medline_journal': 'Am J Physiol Endocrinol Metab', 'ISO_journal': 'Am. J. Physiol. Endocrinol. Metab.', 'authors': ['Krautkramer KA', 'Linnemann AK', 'Fontaine DA', 'Whillock AL', 'Harris TW', 'Schleis GJ', 'Truchan NA', 'Marty-Santos L', 'Lavine JA', 'Cleaver O', 'Kimple ME', 'Davis DB.'], 'DOI_URL': 'https://doi.org/10.1152/ajpendo.00147.2013'}, 'PUB00088919': {'PMID': 1868030, 'ISBN': None, 'volume': '2', 'issue': '4', 'year': 1991, 'title': 'A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor.', 'URL': None, 'raw_pages': '179-86', 'medline_journal': 'Cell Growth Differ', 'ISO_journal': 'Cell Growth Differ.', 'authors': ['Ku DH', 'Chang CD', 'Koniecki J', 'Cannizzaro LA', 'Boghosian-Sell L', 'Alder H', 'Baserga R.'], 'DOI_URL': None}}"	"{'cdd': {'cd15609': 'PHD finger found in Transcription factor 19 (TCF-19) and similar proteins'}}"	"{'name': 'Transcription factor 19, PHD finger', 'short': 'TCF19_PHD'}"	"[{'accession': 'IPR011011', 'name': 'Zinc finger, FYVE/PHD-type', 'type': 'homologous_superfamily'}, {'accession': 'IPR013083', 'name': 'Zinc finger, RING/FYVE/PHD-type', 'type': 'homologous_superfamily'}]"	""	""	"interpro"	"domain"	""
