"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"IPR038294"	"{'subfamilies': 0, 'domain_architectures': 0, 'interactions': 0, 'matches': 3452, 'pathways': 11, 'proteins': 3445, 'proteomes': 1452, 'sets': 0, 'structural_models': {'alphafold': 3174, 'bfvd': 0}, 'structures': 6, 'taxa': 4896}"	"{}"	"[{'text': ""<p>This entry represents the RNA-binding domain of histone RNA hairpin-binding protein, also known as  SLBP [[cite:PUB00070010]]. Proteins containing this domain include SLBP1 and SLBP2 from Xenopus laevis.</p>\r\n\r\n<p>SLBP1 binds the 5' side of the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilising the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE) [[cite:PUB00060526]]. It plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. It stabilises mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression [[cite:PUB00060522], [cite:PUB00060523], [cite:PUB00060524], [cite:PUB00060525]].</p>"", 'llm': False, 'checked': False, 'updated': False}]"	""	""	"{'accession': 'IPR038294', 'name': 'SLBP, RNA-binding domain superfamily', 'type': 'Homologous_superfamily', 'children': []}"	""	False	False	False	"{'PUB00070010': {'PMID': 8957003, 'ISBN': None, 'volume': '10', 'issue': '23', 'year': 1996, 'title': ""The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing."", 'URL': None, 'raw_pages': '3028-40', 'medline_journal': 'Genes Dev', 'ISO_journal': 'Genes Dev.', 'authors': ['Wang ZF', 'Whitfield ML', 'Ingledue TC 3rd', 'Dominski Z', 'Marzluff WF.'], 'DOI_URL': None}, 'PUB00060524': {'PMID': 12588979, 'ISBN': None, 'volume': '23', 'issue': '5', 'year': 2003, 'title': 'Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phase.', 'URL': None, 'raw_pages': '1590-601', 'medline_journal': 'Mol Cell Biol', 'ISO_journal': 'Mol. Cell. Biol.', 'authors': ['Zheng L', 'Dominski Z', 'Yang XC', 'Elms P', 'Raska CS', 'Borchers CH', 'Marzluff WF.'], 'DOI_URL': 'http://dx.doi.org/10.1128/MCB.23.5.1590-1601.2003'}, 'PUB00060525': {'PMID': 19155325, 'ISBN': None, 'volume': '15', 'issue': '3', 'year': 2009, 'title': 'Knockdown of SLBP results in nuclear retention of histone mRNA.', 'URL': None, 'raw_pages': '459-72', 'medline_journal': 'RNA', 'ISO_journal': 'RNA', 'authors': ['Sullivan KD', 'Mullen TE', 'Marzluff WF', 'Wagner EJ.'], 'DOI_URL': 'http://dx.doi.org/10.1261/rna.1205409'}, 'PUB00060522': {'PMID': 18036581, 'ISBN': None, 'volume': '313', 'issue': '1', 'year': 2008, 'title': 'Stem-loop binding protein expressed in growing oocytes is required for accumulation of mRNAs encoding histones H3 and H4 and for early embryonic development in the mouse.', 'URL': None, 'raw_pages': '347-58', 'medline_journal': 'Dev Biol', 'ISO_journal': 'Dev. Biol.', 'authors': ['Arnold DR', 'Francon P', 'Zhang J', 'Martin K', 'Clarke HJ.'], 'DOI_URL': 'http://dx.doi.org/10.1016/j.ydbio.2007.10.032'}, 'PUB00060523': {'PMID': 19470752, 'ISBN': None, 'volume': '29', 'issue': '15', 'year': 2009, 'title': ""Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA."", 'URL': None, 'raw_pages': '4045-56', 'medline_journal': 'Mol Cell Biol', 'ISO_journal': 'Mol. Cell. Biol.', 'authors': ['Yang XC', 'Torres MP', 'Marzluff WF', 'Dominski Z.'], 'DOI_URL': 'http://dx.doi.org/10.1128/MCB.00296-09'}, 'PUB00060526': {'PMID': 11157774, 'ISBN': None, 'volume': '15', 'issue': '2', 'year': 2001, 'title': 'Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression.', 'URL': None, 'raw_pages': '173-87', 'medline_journal': 'Genes Dev', 'ISO_journal': 'Genes Dev.', 'authors': ['Sullivan E', 'Santiago C', 'Parker ED', 'Dominski Z', 'Yang X', 'Lanzotti DJ', 'Ingledue TC', 'Marzluff WF', 'Duronio RJ.'], 'DOI_URL': 'http://dx.doi.org/10.1101/gad.862801'}, 'PUB00060527': {'PMID': 9858606, 'ISBN': None, 'volume': '19', 'issue': '1', 'year': 1999, 'title': ""Two Xenopus proteins that bind the 3' end of histone mRNA: implications for translational control of histone synthesis during oogenesis."", 'URL': None, 'raw_pages': '835-45', 'medline_journal': 'Mol Cell Biol', 'ISO_journal': 'Mol. Cell. Biol.', 'authors': ['Wang ZF', 'Ingledue TC', 'Dominski Z', 'Sanchez R', 'Marzluff WF.'], 'DOI_URL': None}}"	"{'cathgene3d': {'G3DSA:1.10.8.1120': 'Histone RNA hairpin-binding protein RNA-binding domain'}}"	"{'name': 'SLBP, RNA-binding domain superfamily', 'short': 'SLBP_RNA_bind_sf'}"	"[{'accession': 'IPR026502', 'name': 'Histone RNA stem-loop-binding protein SLBP1/SLBP2', 'type': 'family'}, {'accession': 'IPR029344', 'name': 'Histone RNA hairpin-binding protein, RNA-binding domain', 'type': 'domain'}]"	""	""	"interpro"	"homologous_superfamily"	""