General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "IPR025895",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF12544": "Lysine-2,3-aminomutase"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR025895",
            "name": "Lysine-2,3-aminomutase, C-terminal domain",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "Lysine-2,3-aminomutase, C-terminal domain",
            "short": "LAM_C_dom"
        },
        "description": [
            {
                "text": "<p>This domain is found in the C-terminal of lysine-2,3-aminomutase (LAM) and is involved in dimerisation [[cite:PUB00039150]]. LAM catalyses the interconversion of L-alpha-lysine and L-beta-lysine, which proceeds by migration of the amino group from C2 to C3 concomitant with cross-migration of the 3-pro-R hydrogen of L-alpha-lysine to the 2-pro-R position of L-beta-lysine.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00039150": {
                "PMID": 16166264,
                "ISBN": null,
                "volume": "102",
                "issue": "39",
                "year": 2005,
                "title": "The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale.",
                "URL": null,
                "raw_pages": "13819-24",
                "medline_journal": "Proc Natl Acad Sci U S A",
                "ISO_journal": "Proc. Natl. Acad. Sci. U.S.A.",
                "authors": [
                    "Lepore BW",
                    "Ruzicka FJ",
                    "Frey PA",
                    "Ringe D."
                ],
                "DOI_URL": "http://dx.doi.org/10.1073/pnas.0505726102"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 7,
            "interactions": 0,
            "matches": 3564,
            "pathways": 0,
            "proteins": 3564,
            "proteomes": 2172,
            "sets": 0,
            "structural_models": {
                "alphafold": 2847,
                "bfvd": 0
            },
            "structures": 1,
            "taxa": 4527
        },
        "entry_annotations": {
            "alignment:seed": 9,
            "alignment:full": 1476
        },
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "5.4.3.2",
                        "url": "https://enzyme.expasy.org/EC/5.4.3.2"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}