HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "IPR001055",
"entry_id": null,
"type": "family",
"go_terms": [
{
"identifier": "GO:0051537",
"name": "2 iron, 2 sulfur cluster binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0140647",
"name": "P450-containing electron transport chain",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"source_database": "interpro",
"member_databases": {
"panther": {
"PTHR23426": "FERREDOXIN/ADRENODOXIN"
},
"prints": {
"PR00355": "ADRENODOXIN"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR001055",
"name": "Adrenodoxin-like",
"type": "Family",
"children": [
{
"accession": "IPR011536",
"name": "Ferredoxin 2Fe-2S type, proteobacteria",
"type": "Family",
"children": []
}
]
},
"name": {
"name": "Adrenodoxin-like",
"short": "Adrenodoxin-like"
},
"description": [
{
"text": "<p>Adrenodoxin, putidaredoxin, rhodocoxin and terpredoxin are soluble 2Fe-2S iron-sulphur proteins that act as single electron carriers. They are a subgroup of the ferredoxin family of iron-sulphur proteins.</p>\n\n<p>In mitochondrial monooxygenase systems, adrenodoxin transfers an electron from NADPH:adrenodoxin reductase to membrane-bound P450 [[cite:PUB00097471], [cite:PUB00016350]]. In bacteria, putidaredoxin and terpredoxin serve as electron carriers between corresponding NADH-dependent ferredoxin reductases and soluble P450 [[cite:PUB00002613], [cite:PUB00002723]]. The exact functions of other members of this family are not known.</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00002613": {
"PMID": 2180940,
"ISBN": null,
"volume": "265",
"issue": "11",
"year": 1990,
"title": "Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins.",
"URL": null,
"raw_pages": "6066-73",
"medline_journal": "J Biol Chem",
"ISO_journal": "J. Biol. Chem.",
"authors": [
"Peterson JA",
"Lorence MC",
"Amarneh B."
],
"DOI_URL": "http://intl.jbc.org/cgi/content/abstract/265/11/6066"
},
"PUB00002723": {
"PMID": 1629218,
"ISBN": null,
"volume": "267",
"issue": "20",
"year": 1992,
"title": "Cytochrome P-450terp. Isolation and purification of the protein and cloning and sequencing of its operon.",
"URL": null,
"raw_pages": "14193-203",
"medline_journal": "J Biol Chem",
"ISO_journal": "J. Biol. Chem.",
"authors": [
"Peterson JA",
"Lu JY",
"Geisselsoder J",
"Graham-Lorence S",
"Carmona C",
"Witney F",
"Lorence MC."
],
"DOI_URL": "http://intl.jbc.org/cgi/content/abstract/267/20/14193"
},
"PUB00016350": {
"PMID": 12069587,
"ISBN": null,
"volume": "41",
"issue": "25",
"year": 2002,
"title": "A new electron transport mechanism in mitochondrial steroid hydroxylase systems based on structural changes upon the reduction of adrenodoxin.",
"URL": null,
"raw_pages": "7969-78",
"medline_journal": "Biochemistry",
"ISO_journal": "Biochemistry",
"authors": [
"Beilke D",
"Weiss R",
"Lohr F",
"Pristovsek P",
"Hannemann F",
"Bernhardt R",
"Ruterjans H."
],
"DOI_URL": "http://dx.doi.org/10.1021/bi0160361"
},
"PUB00097471": {
"PMID": 22556163,
"ISBN": null,
"volume": "64",
"issue": "6",
"year": 2012,
"title": "Adrenodoxin--a versatile ferredoxin.",
"URL": null,
"raw_pages": "506-12",
"medline_journal": "IUBMB Life",
"ISO_journal": "IUBMB Life",
"authors": [
"Ewen KM",
"Ringle M",
"Bernhardt R."
],
"DOI_URL": null
}
},
"set_info": null,
"overlaps_with": [
{
"accession": "IPR012675",
"name": "Beta-grasp domain superfamily",
"type": "homologous_superfamily"
},
{
"accession": "IPR036010",
"name": "2Fe-2S ferredoxin-like superfamily",
"type": "homologous_superfamily"
}
],
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 24713,
"pathways": 36,
"proteins": 24405,
"proteomes": 11775,
"sets": 0,
"structural_models": {
"alphafold": 19504,
"bfvd": 0
},
"structures": 68,
"taxa": 22841
},
"entry_annotations": {},
"cross_references": {
"prositedoc": {
"displayName": "PROSITE Doc",
"description": "PROSITE is a database of protein families and domains.",
"rank": 18,
"accessions": [
{
"accession": "PDOC00642",
"url": "http://prosite.expasy.org/PDOC00642"
}
]
}
},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "1ayf",
"name": "BOVINE ADRENODOXIN (OXIDIZED)"
}
}
}
