EC 6.4.1.4 - Methylcrotonoyl-CoA carboxylase

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IntEnz Enzyme Nomenclature
EC 6.4.1.4

Names

Accepted name:
methylcrotonoyl-CoA carboxylase
Other names:
β-methylcrotonyl CoA carboxylase
β-methylcrotonyl coenzyme A carboxylase
methylcrotonyl coenzyme A carboxylase
methylcrotonyl-CoA carboxylase
β-methylcrotonyl-CoA carboxylase
Systematic name:
3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)

Reaction

Cofactor

Comments:

A biotinyl-protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00167 , PROSITE:PDOC50975 , PROSITE:PDOC50979 , PROSITE:PDOC50980
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004485
CAS Registry Number: 9023-95-4
UniProtKB/Swiss-Prot: (14) [show] [UniProt]

References

  1. Knappe, J., Schlegel, H.-G. and Lynen, F.
    Zur biochemischen Funktion des Biotins. I. Die Beteilligung der β-Methyl-crotonyl-Carboxylase an der Bildung von β-Hydroxy-β-methyl-glutaryl-CoA from β-Hydroxy-isovaleryl-CoA.
    Biochem. Z. 335: 101-122 (1961). [PMID: 14457200]
  2. Lynen, F., Knappe, J., Lorch, E., Jütting, G., Ringelmann, E. and Lachance, J.-P.
    Zur biochemischen Funktion des Biotins. II. Reinigung und Wirkungsweise der β-Methyl-crotonyl-Carboxlase.
    Biochem. Z. 335: 123-166 (1961). [PMID: 14467590]
  3. Rilling, H.C. and Coon, M.J.
    The enzymatic isomerization of α-methylvinylacetyl coenzyme A and the specificity of a bacterial α-methylcrotonyl coenzyme A carboxylase.
    J. Biol. Chem. 235: 3087-3092 (1960). [PMID: 13741692]
  4. Vagelos, P.
    Regulation of fatty acid biosynthesis.
    Curr. Top. Cell. Regul. 4: 119-166 (1971).

[EC 6.4.1.4 created 1961]