EC 6.3.4.17 - Formate—dihydrofolate ligase

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IntEnz Enzyme Nomenclature
EC 6.3.4.17

Names

Accepted name:
formate—dihydrofolate ligase
Other names:
dihydrofolate formyltransferase
formyl dihydrofolate synthase
Systematic name:
formate:dihydrofolate ligase (ADP-forming)

Reaction

Comments:

Not identical with EC 6.3.4.3 (formate—tetrahydrofolate ligase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047897
CAS Registry Number: 123303-25-3

References

  1. Drake, J.C., Baram, J. and Allegra, C.J.
    Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells.
    Biochem. Pharmacol. 39: 615-618 (1990). [PMID: 2306274]

[EC 6.3.4.17 created 1992]