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EC 5.4.99.2 - Methylmalonyl-CoA mutase

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IntEnz Enzyme Nomenclature
EC 5.4.99.2

Names

Accepted name:

methylmalonyl-CoA mutase

Other names:

(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase [incorrect]
(S)-methylmalonyl-CoA mutase
methylmalonyl coenzyme A carbonylmutase
methylmalonyl coenzyme A mutase
methylmalonyl-CoA CoA-carbonyl mutase

Systematic name:

(R)-methylmalonyl-CoA CoA-carbonylmutase

Reaction

22888 [IUBMB]

(R)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

Name origin: UniProt - CHECKED (C)

CHEBI:57326

Formula: C25H35N7O19P3S
Charge: -5

ChEBI compound status: CHECKED (C)

=

succinyl-CoA

succinyl-CoA

Name origin: UniProt - CHECKED (C)

CHEBI:57292

Formula: C25H35N7O19P3S
Charge: -5

ChEBI compound status: CHECKED (C)

Cofactor

cob(II)alamin

Comments:

Requires a cobamide coenzyme.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UM-BBD , UniPathway

Protein domains and families: PROSITE:PDOC00470

Structural data: CSA , EC2PDB

Gene Ontology: GO:0004494

CAS Registry Number: 9023-90-9

UniProtKB/Swiss-Prot: (22) [show] [UniProt]

References

Barker, H.A.

Coenzyme B₁₂-dependent mutases causing carbon chain rearrangements.

In: Boyer, P.D. (Ed.) The Enzymes , 3rd ed. vol. 6 , Academic Press , New York , 1972 , 509-537

[EC 5.4.99.2 created 1961, modified 1983, modified 2004]

EC 5 - Isomerases

EC 5.4 - Intramolecular transferases