EC 5.1.99.4 - α-methylacyl-CoA racemase

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IntEnz Enzyme Nomenclature
EC 5.1.99.4

Names

Accepted name:
α-methylacyl-CoA racemase
Systematic name:
2-methylacyl-CoA 2-epimerase

Reaction

Comments:

α-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008111
UniProtKB/Swiss-Prot:

References

  1. Schmitz, W., Fingerhut, R., Conzelmann, E.
    Purification and properties of an α-methylacyl-CoA racemase from rat liver.
    Eur. J. Biochem. 222: 313-323 (1994). [PMID: 8020470]

[EC 5.1.99.4 created 1999]