EC 4.1.2.33 - Fucosterol-epoxide lyase

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IntEnz Enzyme Nomenclature
EC 4.1.2.33

Names

Accepted name:
fucosterol-epoxide lyase
Other names:
(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase
(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)
Systematic name:
(24R,241R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)

Reaction

Comments:

The insect enzyme is involved in the conversion of sitosterol into cholesterol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047906
CAS Registry Number: 99676-42-3

References

  1. Prestwich, G.D., Angelastro, M., De Palma, A. and Perino, M.A.
    Fucosterol epoxide lyase of insects: synthesis of labeled substrates and development of a partition assay.
    Anal. Biochem. 151: 315-326 (1985). [PMID: 3913328]

[EC 4.1.2.33 created 1989, modified 2013]