EC 2.4.2.20 - Dioxotetrahydropyrimidine phosphoribosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.2.20

Names

Accepted name:
dioxotetrahydropyrimidine phosphoribosyltransferase
Other names:
dioxotetrahydropyrimidine phosphoribosyl transferase
dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase
dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase
dioxotetrahydropyrimidine-ribonucleotide diphosphorylase
2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-α-D-ribosyltransferase
Systematic name:
2,4-dioxotetrahydropyrimidine-D-ribonucleotide:diphosphate phospho-α-D-ribosyltransferase

Reaction

Comments:

Acts (in the reverse direction) on uracil and other pyrimidines and pteridines containing a 2,4-diketo structure.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047281
CAS Registry Number: 37277-75-1

References

  1. Hatfield, D. and Wyngaarden, J.B.
    3-Ribosylpurines. I. Synthesis of (3-ribosyluric acid) 5'-phosphate and (3-ribosylxanthine) 5'-phosphate by a pyrimidine ribonucleotide pyrophosphorylase of beef erythrocytes.
    J. Biol. Chem. 239: 2580-2586 (1964). [PMID: 14235538]

[EC 2.4.2.20 created 1972]