EC 1.3.8.15 - 3-(aryl)acrylate reductase

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IntEnz Enzyme Nomenclature
EC 1.3.8.15

Names

Accepted name:
3-(aryl)acrylate reductase
Systematic name:
3-(phenyl)propanoate:electron-transfer flavoprotein 2,3-oxidoreductase

Reactions

Comments:

The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan. Unlike EC 1.3.1.31, 2-enoate reductase, this enzyme has minimal activity with crotonate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Dodd, D., Spitzer, M. H., Van Treuren, W., Merrill, B. D., Hryckowian, A. J., Higginbottom, S. K., Le, A., Cowan, T. M., Nolan, G. P., Fischbach, M. A., Sonnenburg, J. L.
    A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites.
    Nature 551 : 648-652 (2017). [PMID: 29168502]

[EC 1.3.8.15 created 2019]