EC 7.6.2.15 - ABC-type thiamine transporter

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IntEnz Enzyme Nomenclature
EC 7.6.2.15

Names

Accepted name:
ABC-type thiamine transporter
Other names:
thiamin transporting ATPase
thiamine ABC transporter
thiamin ABC transporter
thiamine transporting ATPase
Systematic name:
ATP phosphohydrolase (ABC-type, thiamine-importing)

Reaction

Comments:

ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Webb, E., Claas, K., Downs, D.
    thiBPQ encodes an ABC transporter required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium.
    J. Biol. Chem. 273: 8946-8950 (1998). [PMID: 9535878]

[EC 7.6.2.15 created 2019]