EC 1.14.11.64 - Glutarate dioxygenase

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ENZYME: 1.14.11.64


ID   1.14.11.64
DE   Glutarate dioxygenase.
CA   Glutarate + 2-oxoglutarate + O(2) = (S)-2-hydroxyglutarate + succinate +
CA   CO(2).
CC   -!- Requires iron(II).
CC   -!- The enzyme, characterized from the bacteria Escherichia coli and
CC       Pseudomonas putida, participates in L-lysine degradation in many
CC       bacteria.
CC   -!- It provides an alternative route for L-glutarate degradation that
CC       does not proceed via CoA-activated intermediates.
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