EC 7.4.2.10 - ABC-type glutathione transporter

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IntEnz Enzyme Nomenclature
EC 7.4.2.10

Names

Accepted name:
ABC-type glutathione transporter
Other names:
glutathione transporting ATPase
glutathione ABC transporter
Systematic name:
ATP phosphohydrolase (ABC-type,glutathione-importing)

Reaction

Comments:

A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (16) [show] [UniProt]

References

  1. Suzuki, H., Koyanagi, T., Izuka, S., Onishi, A., Kumagai, H.
    The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
    J. Bacteriol. 187: 5861-5867 (2005). [PMID: 16109926]
  2. Moussatova, A., Kandt, C., O'Mara, M. L., Tieleman, D. P.
    ATP-binding cassette transporters in Escherichia coli.
    Biochim. Biophys. Acta 1778: 1757-1771 (2008). [PMID: 18634750]

[EC 7.4.2.10 created 2019]