EC 6.2.1.56 - 4-hydroxybutyrate—CoA ligase (ADP-forming)

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IntEnz Enzyme Nomenclature
EC 6.2.1.56

Names

Accepted name:
4-hydroxybutyrate—CoA ligase (ADP-forming)
Systematic name:
4-hydroxybutanoate:CoA ligase (ADP-forming)

Reaction

Comments:

The enzyme, characterized from the marine ammonia-oxidizing archaeon Nitrosopumilus maritimus, participates in a variant of the 3-hydroxypropanoate/4-hydroxybutanate CO2 fixation cycle. cf. EC 6.2.1.40, 4-hydroxybutyrate—CoA ligase (AMP-forming).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Konneke, M., Schubert, D. M., Brown, P. C., Hugler, M., Standfest, S., Schwander, T., Schada von Borzyskowski, L., Erb, T. J., Stahl, D. A., Berg, I. A.
    Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO2 fixation.
    Proc. Natl. Acad. Sci. U.S.A. 111: 8239-8244 (2014). [PMID: 24843170]

[EC 6.2.1.56 created 2019]