EC 2.1.1.54 - Deoxycytidylate C-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.54

Names

Accepted name:
deoxycytidylate C-methyltransferase
Other names:
dCMP methyltransferase
deoxycytidylate methyltransferase
Systematic name:
5,10-methylenetetrahydrofolate:dCMP C-methyltransferase

Reaction

Comments:

dCMP is methylated by formaldehyde in the presence of tetrahydrofolate. CMP, dCTP and CTP can act as acceptors, but more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050003
CAS Registry Number: 61970-01-2

References

  1. Kuo, T.-T. and Tu, J.
    Enzymatic synthesis of deoxy-5-methyl-cytidylic acid replacing deoxycytidylic acid in Xanthomonas oryzae phage Xp12DNA.
    Nature 263: 615 (1976). [PMID: 980110]

[EC 2.1.1.54 created 1978]