EC 7.2.2.6 - P-type K+ transporter

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IntEnz Enzyme Nomenclature
EC 7.2.2.6

Names

Accepted name:
P-type K+ transporter
Other names:
K+-translocating Kdp-ATPase
multi-subunit K+-transport ATPase
potassium-importing ATPase
K+-transporting ATPase
K+-importing ATPase
Systematic name:
ATP phosphohydrolase (P-type, K+-importing)

Reaction

Cofactor

Comments:

A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme that is involved in K+ import. The probable stoichiometry is one ion per ATP hydrolysed. Formerly EC 3.6.3.12.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00139
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008556
UniProtKB/Swiss-Prot: (121) [show] [UniProt]

References

  1. Siebers, A. and Altendorf, K.
    Characterization of the phosphorylated intermediate of the K+-translocating Kdp-ATPase from Escherichia coli.
    J. Biol. Chem 264: 5831-5838 (1989). [PMID: 2522440]
  2. Gassel, M., Siebers, A., Epstein, W. and Altendorf, K.
    Assembly of the Kdp complex, the multi-subunit K+-transport ATPase of Escherichia coli.
    Biochim. Biophys. Acta 1415: 77-84 (1998). [PMID: 9858692]
  3. Huang, C. S., Pedersen, B. P., Stokes, D. L.
    Crystal structure of the potassium-importing KdpFABC membrane complex.
    Nature 546: 681-685 (2017). [PMID: 28636601]

[EC 7.2.2.6 created 2000 as EC 3.6.3.12, transferred 2018 to EC 7.2.2.6]