EC - ABC-type phosphate transporter

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IntEnz Enzyme Nomenclature


Accepted name:
ABC-type phosphate transporter
Other names:
ABC phosphate transporter
phosphate-transporting ATPase [ambiguous]
Systematic name:
ATP phosphohydrolase (ABC-type, phosphate-importing)



An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of phosphate anions. Unlike P-type ATPases, it does not undergo phosphorylation during the transport process. Formerly EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00185
Structural data: CSA , EC2PDB
Gene Ontology: GO:0015415
UniProtKB/Swiss-Prot: (381) [show] [UniProt]


  1. Webb, D.C., Rosenberg, H. and Cox, G.B.
    Mutational analysis of the Escherichia coli phosphate-specific transport system, a member of the traffic ATPase (or ABC) family of membrane transporters. A role for proline residues in transmembrane helices.
    J. Biol. Chem. 267: 24661-24668 (1992). [PMID: 1447208]
  2. Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr.
    Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.
    Res. Microbiol. 146: 271-278 (1995). [PMID: 7569321]
  3. Braibant, M., LeFevre, P., de Wit, L., Ooms, J., Peirs, P., Huygen, K., Wattiez, R. and Content, J.
    Identification of a second Mycobacterium tuberculosis gene cluster encoding proteins of an ABC phosphate transporter.
    FEBS Lett. 394: 206-212 (1996). [PMID: 8843165]
  4. Saier, M.H., Jr.
    Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
    Adv. Microb. Physiol. 40: 81-136 (1998). [PMID: 9889977]
  5. Griffiths, J.K. and Sansom, C.E.
    The Transporter Factsbook, Academic Press, San Diego, 1998

[EC created 2000 as EC, transferred 2018 to EC]