EC 2.1.1.28 - Phenylethanolamine N-methyltransferase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.1.1.28
Names
Accepted name:
phenylethanolamine N-methyltransferase
Other
names:
noradrenalin N-methyltransferase
noradrenaline N-methyltransferase
norepinephrine N-methyltransferase
norepinephrine methyltransferase
phenethanolamine N-methyltransferase
phenethanolamine methyltransferase
noradrenaline N-methyltransferase
norepinephrine N-methyltransferase
norepinephrine methyltransferase
phenethanolamine N-methyltransferase
phenethanolamine methyltransferase
Systematic name:
S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase
Reactions
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12176 [IUBMB]phenylethanolamineName origin: UniProt - CHECKED (C)Formula: C8H12NO
Charge: 1ChEBI compound status: CHECKED (C)S-adenosyl-L-methionineName origin: UniProt - CHECKED (C)Formula: C15H23N6O5S
Charge: 1ChEBI compound status: CHECKED (C)=H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)N-methylphenylethanolamineName origin: UniProt - CHECKED (C)Formula: C9H14NO
Charge: 1ChEBI compound status: CHECKED (C) -
(R)-noradrenalineName origin: UniProt - CHECKED (C)Formula: C8H12NO3
Charge: 1ChEBI compound status: CHECKED (C)S-adenosyl-L-methionineName origin: UniProt - CHECKED (C)Formula: C15H23N6O5S
Charge: 1ChEBI compound status: CHECKED (C)=(R)-adrenalineName origin: UniProt - CHECKED (C)Formula: C9H14NO3
Charge: 1ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
Acts on various phenylethanolamines; converts noradrenaline into adrenaline.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Protein domains and families:
PROSITE:PDOC00844
Gene Ontology:
GO:0004603
CAS Registry Number:
9037-68-7
UniProtKB/Swiss-Prot:
References
-
Purification and properties of phenylethanolamine-N-methyl transferase.J. Biol. Chem. 237 : 1657-1660 (1962).
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Purification and properties of bovine phenylethanolamine N-methyltransferase.J. Biol. Chem. 245 : 329-334 (1970). [PMID: 5412063]
[EC 2.1.1.28 created 1972]