EC 2.4.2.59 - Sulfide-dependent adenosine diphosphate thiazole synthase

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ENZYME: 2.4.2.59


ID   2.4.2.59
DE   Sulfide-dependent adenosine diphosphate thiazole synthase.
CA   NAD(+) + glycine + sulfide = nicotinamide + ADP-5-ethyl-4-methylthiazole-
CA   2-carboxylate + 3 H(2)O.
CC   -!- This iron dependent enzyme, found in most archaea, is involved in the
CC       biosynthesis of thiamine phosphate.
CC   -!- The homologous enzyme from plants and fungi (EC 2.4.2.60) uses an
CC       intrinsic cysteine as sulfur donor and, unlike the archaeal enzyme,
CC       is a single turn-over enzyme.
DR   Q9Y9Z0    , THI4_AERPE ;  O29556    , THI4_ARCFU ;  C4XIR5    , THI4_DESMR ;
DR   A8ZVP3    , THI4_DESOH ;  A7HMY3    , THI4_FERNB ;  Q3V7Z9    , THI4_HALMA ;
DR   B0R884    , THI4_HALS3 ;  Q9HMC7    , THI4_HALSA ;  Q18KP1    , THI4_HALWD ;
DR   A6UV59    , THI4_META3 ;  Q8TM19    , THI4_METAC ;  Q46AR1    , THI4_METBF ;
DR   Q12U93    , THI4_METBU ;  F6BCS4    , THI4_METIK ;  Q58018    , THI4_METJA ;
DR   A4FWG7    , THI4_METM5 ;  A9A9W1    , THI4_METM6 ;  A6VGT9    , THI4_METM7 ;
DR   Q8Q0B5    , THI4_METMA ;  A3CXS4    , THI4_METMJ ;  Q6LXJ8    , THI4_METMP ;
DR   A4YIV7    , THI4_METS5 ;  O27657    , THI4_METTH ;  A0B880    , THI4_METTP ;
DR   A6UPZ7    , THI4_METVS ;  Q3IMI0    , THI4_NATPD ;  Q9V0J8    , THI4_PYRAB ;
DR   Q8ZZM5    , THI4_PYRAE ;  A4WKY7    , THI4_PYRAR ;  A3MWF6    , THI4_PYRCJ ;
DR   Q8U0Q5    , THI4_PYRFU ;  O59082    , THI4_PYRHO ;  A1RW13    , THI4_PYRIL ;
DR   B1YDX0    , THI4_PYRNV ;  Q97ZY5    , THI4_SACS2 ;  Q4JAF8    , THI4_SULAC ;
DR   C3N6N6    , THI4_SULIA ;  C4KIA7    , THI4_SULIK ;  C3MQY1    , THI4_SULIL ;
DR   C3MWW9    , THI4_SULIM ;  C3NGI6    , THI4_SULIN ;  C3N749    , THI4_SULIY ;
DR   Q975R0    , THI4_SULTO ;  Q5JD25    , THI4_THEKO ;  Q9WZP4    , THI4_THEMA ;
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