EC 1.14 - Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2
EC 188.8.131.52 - (R)-limonene 6-monooxygenase
IntEnz Enzyme Nomenclature
- (+)-(R)-limonene + reduced NADPHhemoprotein reductase + O2 = (+)-trans-carveol + oxidized NADPHhemoprotein reductase + H2O
The reaction is stereospecific with over 95% yield of (+)-trans-carveol from (R)-limonene. (S)-Limonene, the substrate for EC 184.108.40.206, (S)-limonene 6-monooxygenase, is not a substrate. Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds.
Links to other databases
Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development.Plant Physiol. 117 : 901-912 (1998). [PMID: 9662532]
Cytochrome P-450 dependent (+)-limonene-6-hydroxylation in fruits of caraway (Carum Carvi).Phytochemistry 50 : 243-248 (1999).
[EC 220.127.116.11 created 2003 as EC 18.104.22.168, transferred 2017 to EC 22.214.171.124]