EC 6.2.1.47 - Medium-chain-fatty-acid—[acyl-carrier-protein] ligase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 6.2.1.47

Names

Accepted name:
medium-chain-fatty-acid—[acyl-carrier-protein] ligase
Other name:
jamA (gene name)
Systematic name:
medium-chain-fatty-acid:[acyl-carrier protein] ligase (AMP-forming)

Reaction

Comments:

The enzyme ligates medium chain fatty acids (with aliphatic chain of 6-12 carbons) to an acyl-carrier protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Edwards, D. J., Marquez, B. L., Nogle, L. M., McPhail, K., Goeger, D. E., Roberts, M. A., Gerwick, W. H.
    Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula.
    Chem. Biol. 11 : 817-833 (2004). [PMID: 15217615]
  2. Zhu, X., Liu, J., Zhang, W.
    De novo biosynthesis of terminal alkyne-labeled natural products.
    Nat. Chem. Biol. 11 : 115-120 (2015). [PMID: 25531891]

[EC 6.2.1.47 created 2016]