EC 5.1.3.35 - 2-epi-5-epi-valiolone 7-phosphate 2-epimerase

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IntEnz Enzyme Nomenclature
EC 5.1.3.35

Names

Accepted name:
2-epi-5-epi-valiolone 7-phosphate 2-epimerase
Other name:
AcbO
Systematic name:
2-epi-5-epi-valiolone-7-phosphate 2-epimerase

Reaction

Comments:

The enzyme, isolated from the bacterium Actinoplanes sp. SE 50/110, is involved in the biosynthesis of the α-glucosidase inhibitor acarbose.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Zhang, C. S., Podeschwa, M., Altenbach, H. J., Piepersberg, W., Wehmeier, U. F.
    The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase.
    FEBS Lett. 540: 47-52 (2003). [PMID: 12681481]

[EC 5.1.3.35 created 2015]