EC - R-phycocyanin α-cysteine-84 phycourobilin lyase/isomerase

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IntEnz Enzyme Nomenclature


Accepted name:
R-phycocyanin α-cysteine-84 phycourobilin lyase/isomerase
Other name:
rpcG (gene name)
Systematic name:
[R-phycocyanin α-subunit]-Cys84-phycourobilin:(2R,3E)-phycoerythrobilin lyase/isomerase



The enzyme, characterized from the cyanobacterium Synechococcus sp. WH8102, catalyses the covalent attachment of the phycobilin chromophore phycoerythrobilin to cysteine 84 of the α subunit of the phycobiliprotein R-phycocyanin and its isomerization to phycourobilin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Blot, N., Wu, X. J., Thomas, J. C., Zhang, J., Garczarek, L., Bohm, S., Tu, J. M., Zhou, M., Ploscher, M., Eichacker, L., Partensky, F., Scheer, H., Zhao, K. H.
    Phycourobilin in trichromatic phycocyanin from oceanic cyanobacteria is formed post-translationally by a phycoerythrobilin lyase-isomerase.
    J. Biol. Chem. 284: 9290-9298 (2009). [PMID: 19182270]

[EC created 2015]