EC 1.3.8.12 - (2S)-methylsuccinyl-CoA dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.3.8.12

Names

Accepted name:
(2S)-methylsuccinyl-CoA dehydrogenase
Other name:
Mcd
Systematic name:
(2S)-methylsuccinyl-CoA:electron-transfer flavoprotein oxidoreductase

Reaction

Cofactor

Comments:

The enzyme, characterized from the bacterium Rhodobacter sphaeroides, is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Erb, T. J., Fuchs, G., Alber, B. E.
    (2S)-Methylsuccinyl-CoA dehydrogenase closes the ethylmalonyl-CoA pathway for acetyl-CoA assimilation.
    Mol. Microbiol. 73: 992-1008 (2009). [PMID: 19703103]

[EC 1.3.8.12 created 2015]