EC 6.3.2.44 - Pantoate—β-alanine ligase (ADP-forming)

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IntEnz Enzyme Nomenclature
EC 6.3.2.44

Names

Accepted name:
pantoate—β-alanine ligase (ADP-forming)
Other names:
pantothenate synthetase [ambiguous]
pantoate—β-alanine ligase [ambiguous]
Systematic name:
(R)-pantoate:β-alanine ligase (ADP-forming)

Reaction

Comments:

The enzyme, characterized from the archaeon Methanosarcina mazei, is involved in the biosynthesis of pantothenate. It is different from EC 6.3.2.1, the AMP-forming pantoate-β-alanine ligase found in bacteria and eukaryota. Formerly EC 6.3.2.n5.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ronconi, S., Jonczyk, R., Genschel, U.
    A novel isoform of pantothenate synthetase in the Archaea.
    FEBS J. 275: 2754-2764 (2008). [PMID: 18422645]

[EC 6.3.2.44 created 2014]