EC 2.8.2.37 - Trehalose 2-sulfotransferase

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IntEnz Enzyme Nomenclature
EC 2.8.2.37

Names

Accepted name:
trehalose 2-sulfotransferase
Other name:
Stf0 sulfotransferase
Systematic name:
3'-phosphoadenylyl-sulfate:α,α-trehalose 2-sulfotransferase

Reaction

Comments:

The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Mougous, J. D., Petzold, C. J., Senaratne, R. H., Lee, D. H., Akey, D. L., Lin, F. L., Munchel, S. E., Pratt, M. R., Riley, L. W., Leary, J. A., Berger, J. M., Bertozzi, C. R.
    Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.
    Nat. Struct. Mol. Biol. 11: 721-729 (2004). [PMID: 15258569]
  2. Pi, N., Hoang, M. B., Gao, H., Mougous, J. D., Bertozzi, C. R., Leary, J. A.
    Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry.
    Anal. Biochem. 341: 94-104 (2005). [PMID: 15866533]

[EC 2.8.2.37 created 2014]