EC - Adenylate dimethylallyltransferase (ADP/ATP-dependent)

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IntEnz Enzyme Nomenclature


Accepted name:
adenylate dimethylallyltransferase (ADP/ATP-dependent)
Other names:
cytokinin synthase [ambiguous]
isopentenyltransferase [ambiguous]
2-isopentenyl-diphosphate:ADP/ATP Δ2-isopentenyltransferase
adenylate isopentenyltransferase [ambiguous]
dimethylallyl diphosphate:ATP/ADP isopentenyltransferase
Systematic name:
dimethylallyl-diphosphate:ADP/ATP dimethylallyltransferase



Involved in the biosynthesis of cytokinins in plants. The IPT4 isoform from the plant Arabidopsis thaliana is specific for ADP and ATP [1]. Other isoforms, such as IPT1 from Arabidopsis thaliana [1,2] and the enzyme from the common hop, Humulus lupulus [3], also have a lower activity with AMP (cf. EC, adenylate dimethylallyltransferase (AMP-dependent)).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Kakimoto, T.
    Identification of plant cytokinin biosynthetic enzymes as dimethylallyl diphosphate:ATP/ADP isopentenyltransferases.
    Plant Cell Physiol. 42: 677-685 (2001). [PMID: 11479373]
  2. Takei, K., Sakakibara, H., Sugiyama, T.
    Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.
    J. Biol. Chem. 276: 26405-26410 (2001). [PMID: 11313355]
  3. Sakano, Y., Okada, Y., Matsunaga, A., Suwama, T., Kaneko, T., Ito, K., Noguchi, H., Abe, I.
    Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).
    Phytochemistry 65: 2439-2446 (2004). [PMID: 15381407]

[EC created 2013]