EC 2.1.1.278 - Indole-3-acetate O-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.278

Names

Accepted name:
indole-3-acetate O-methyltransferase
Other names:
IAA carboxylmethyltransferase
IAMT
Systematic name:
S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase

Reaction

Cofactor

Comments:

Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0103007
UniProtKB/Swiss-Prot:

References

  1. Zubieta, C., Ross, J. R., Koscheski, P., Yang, Y., Pichersky, E., Noel, J. P.
    Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
    Plant Cell 15: 1704-1716 (2003). [PMID: 12897246]
  2. Li, L., Hou, X., Tsuge, T., Ding, M., Aoyama, T., Oka, A., Gu, H., Zhao, Y., Qu, L. J.
    The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.
    Plant Cell Rep. 27: 575-584 (2008). [PMID: 17926040]
  3. Zhao, N., Ferrer, J. L., Ross, J., Guan, J., Yang, Y., Pichersky, E., Noel, J. P., Chen, F.
    Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
    Plant Physiol. 146: 455-467 (2008). [PMID: 18162595]

[EC 2.1.1.278 created 2013]