EC 2.3.2.20 - Cyclo(L-leucyl-L-phenylalanyl) synthase

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ENZYME: 2.3.2.20


ID   2.3.2.20
DE   Cyclo(L-leucyl-L-phenylalanyl) synthase.
CA   L-leucyl-tRNA(Leu) + L-phenylalanyl-tRNA(Phe) = tRNA(Leu) + tRNA(Phe) +
CA   cyclo(L-leucyl-L-phenylalanyl).
CC   -!- The reaction proceeds following a ping-pong mechanism forming a
CC       covalent intermediate between an active site serine and the
CC       L-phenylalanine residue.
CC   -!- The protein, found in the bacterium Streptomyces noursei, also forms
CC       cyclo(L-phenylalanyl-L-phenylalanyl), cyclo(L-methionyl-L-
CC       phenylalanyl), cyclo(L-phenylalanyl-L-tyrosyl) and cyclo(L-methionyl-
CC       L-tyrosyl).
DR   Q8GED7    , CLPS_STRNR ;
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