EC 2.3.1.219 - Demethoxycurcumin synthase

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ENZYME: 2.3.1.219


ID   2.3.1.219
DE   Demethoxycurcumin synthase.
CA   (1) 4-coumaroyl-CoA + feruloylacetyl-CoA + H(2)O = 2 CoA +
CA   demethoxycurcumin + CO(2).
CA   (2) 4-coumaroyl-CoA + (4-coumaroyl)acetyl-CoA + H(2)O = 2 CoA +
CA   bisdemethoxycurcumin + CO(2).
CC   -!- A polyketide synthase from the plant Curcuma longa (turmeric).
CC   -!- Three isoforms exist, CURS1, CURS2 and CURS3.
CC   -!- While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate (cf.
CC       EC 2.3.1.217), CURS3 can accept 4-coumaroyl-CoA equally well.
DR   C6L7V9    , CURS3_CURLO;
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