EC 2.1.1.238 - Mycinamicin VI 2''-O-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.238

Names

Accepted name:
mycinamicin VI 2''-O-methyltransferase
Other name:
MycE
Systematic name:
S-adenosyl-L-methionine:mycinamicin VI 2''-O-methyltransferase

Reaction

Comments:

The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics. Requires Mg2+ for optimal activity.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102302
UniProtKB/Swiss-Prot:

References

  1. Li, S., Anzai, Y., Kinoshita, K., Kato, F., Sherman, D. H.
    Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.
    Chembiochem 10: 1297-1301 (2009). [PMID: 19415708]

[EC 2.1.1.238 created 2011]