EC 2.1.1.230 - 23S rRNA (adenosine1067-2'-O)-methyltransferase

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ENZYME: 2.1.1.230


ID   2.1.1.230
DE   23S rRNA (adenosine(1067)-2'-O)-methyltransferase.
AN   23S rRNA A(1067) 2'-methyltransferase.
AN   Nosiheptide-resistance methyltransferase.
AN   Thiostrepton-resistance methylase.
CA   S-adenosyl-L-methionine + adenosine(1067) in 23S rRNA = S-adenosyl-L-
CA   homocysteine + 2'-O-methyladenosine(1067) in 23S rRNA.
CC   -!- The methylase that is responsible for autoimmunity in the
CC       thiostrepton producer Streptomyces azureus, renders ribosomes
CC       completely resistant to thiostrepton.
CC   -!- Formerly EC 2.1.1.66.
DR   P52391    , NSHR_STRAS ;  P18644    , TSNR_STRAJ ;  P52393    , TSNR_STRLU ;
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