EC - S-methyl-5'-thioadenosine deaminase

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IntEnz Enzyme Nomenclature


Accepted name:
S-methyl-5'-thioadenosine deaminase
Other names:
MTA deaminase
5-methylthioadenosine deaminase
Systematic name:
S-methyl-5'-thioadenosine amidohydrolase



The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC and has some activity against adenosine. Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are not substrates. Formerly EC 3.5.4.n1.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (59) [show] [UniProt]


  1. Hermann, J. C., Marti-Arbona, R., Fedorov, A. A., Fedorov, E., Almo, S. C., Shoichet, B. K., Raushel, F. M.
    Structure-based activity prediction for an enzyme of unknown function.
    Nature 448: 775-779 (2007). [PMID: 17603473]

[EC created 2011]