EC 4.3.1.16 - threo-3-hydroxy-L-aspartate ammonia-lyase

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IntEnz Enzyme Nomenclature
EC 4.3.1.16

Names

Accepted name:
threo-3-hydroxy-L-aspartate ammonia-lyase
Other names:
L-threo-3-hydroxyaspartate dehydratase
threo-3-hydroxyaspartate dehydratase
Systematic name:
threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Pseudomonas sp. T62, is highly specific, and does not accept any other stereoisomer of 3-hydroxyaspartate. Different from EC 4.3.1.20, erythro-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.27, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, or Ca2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030848
UniProtKB/Swiss-Prot:

References

  1. Wada, M., Matsumoto, T., Nakamori, S., Sakamoto, M., Kataoka, M., Liu, J.-Q., Itoh, N., Yamada, H. and Shimizu, S.
    Purification and characterization of a novel enzyme, L-threo-3-hydroxyaspartate dehydratase, from Pseudomonas sp. T62.
    FEMS Microbiol. Lett. 179 : 147-151 (1999). [PMID: 10481099]

[EC 4.3.1.16 created 2001, modified 2010]