EC 1.2.1.80 - Long-chain acyl-[acyl-carrier-protein] reductase

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IntEnz Enzyme Nomenclature
EC 1.2.1.80

Names

Accepted name:
long-chain acyl-[acyl-carrier-protein] reductase
Other names:
long-chain acyl-[acp] reductase
fatty acyl-[acyl-carrier-protein] reductase
acyl-[acp] reductase
Systematic name:
long-chain-aldehyde:NAD(P)+ oxidoreductase (acyl-[acyl-carrier protein]-forming)

Reactions

Cofactor

Comments:

Catalyses the reaction in the opposite direction. This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde. Together with EC 4.1.99.5, octadecanal decarbonylase, it is involved in alkane biosynthesis. The natural substrates of the enzyme are C16 to C18 activated fatty acids. Requires Mg2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Schirmer, A., Rude, M. A., Li, X., Popova, E., del Cardayre, S. B.
    Microbial biosynthesis of alkanes.
    Science 329: 559-562 (2010). [PMID: 20671186]

[EC 2.1.2.80 created 2010]