EC - L-serine-phosphatidylethanolamine phosphatidyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
L-serine-phosphatidylethanolamine phosphatidyltransferase
Other names:
phosphatidylserine synthase 2
serine-exchange enzyme II
Systematic name:
L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase



This mammalian enzyme catalyses an exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (15) [show] [UniProt]


  1. Stone, S. J., Vance, J. E.
    Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2.
    Biochem. J. 342: 57-64 (1999). [PMID: 10432300]
  2. Tomohiro, S., Kawaguti, A., Kawabe, Y., Kitada, S., Kuge, O.
    Purification and characterization of human phosphatidylserine synthases 1 and 2.
    Biochem. J. 418: 421-429 (2009). [PMID: 19014349]

[EC created 2010]